The canine distemper vaccine is typically given in some variation of a combination vaccine that also protects your pet from several other serious diseases, such as parvovirus infection. Many of the diseases that are prevented by this combination vaccine have no effective treatment other than supportive care; however, vaccination can prevent these diseases or minimize the signs of illness. Other vaccines, such as the rabies and Bordetella vaccines, may be given in addition to the canine distemper/parvo combination vaccine.